Thanks for the excellent response. I can imagine how misguided over-generous funding can accelerate research to wrong direction. If I interpreted it correctly,

Thanks for the excellent response. I can imagine how misguided over-generous funding can accelerate research to wrong direction. If I interpreted it correctly, one of the biggest weakness is that not enough effort is to put to verify findings of genome analysis in real biological setup. Is it because funding for genome sequencing and analysis has grown in over-proportion compared to more traditional clinical research or that the need for this is not realized in genome analysis circles or something else? Btw. Can you elaborate on the following excerpt. Is there specific problems in genome analysis techniques that make it harder to nail down correct variants? our tools for measuring genotypes are too imprecise and too expensive to support experiments which will nail down exactly which variants are contributing to a given disease