4 ms·
Possible but untested. You may be interested to see this recent study that draws a mechanistic link (broadly, microglial inflammation) between the symptoms of l
by cqz 3y ago
Possible but untested. You may be interested to see this recent study that draws a mechanistic link (broadly, microglial inflammation) between the symptoms of long covid and "chemobrain" following chemotherapy [0]. The authors do suggest treatments proposed to restore cognition post-chemotherapy may also be applicable to long covid, e.g. metformin [1].
[0] https://www.cell.com/cell/fulltext/S0092-8674(22)00713-9 https://www.cell.com/cell/fulltext/S0092-8674(22)00713-9
[1] https://www.nature.com/articles/s41591-020-0985-2 https://www.nature.com/articles/s41591-020-0985-2
- thenerdhead 3y agoMetformin is looking like the aspirin of the 21st century.
- vonnik 3y agoNir Barzilai and a team of researchers are leading a large clinical trial to test the benefits of metformin in slowing the aging process, which is upstream of so many diseases that yeah, it could just be a cheap cure-all. Sadly requires a prescription in the US. But berberine is the off-the-shelf equivalent. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347426/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347426/
- thenerdhead 3y agoYeah agreed. Is berberine really an equivalent though if the mechanisms are different and the not knowing metformin’s complete mechanism although it has a pleitropic effect? Metformin is heavily studied in comparison too.