I have been looking at Python GUI libraries/frameworks/services over the past > 1 year. I'll cut straight to the chase with my recommendations for what they are

I have been looking at Python GUI libraries/frameworks/services over the past > 1 year. I'll cut straight to the chase with my recommendations for what they are worth. - NiceGUI https://nicegui.io/#features https://nicegui.io/#features - my favorite of the bunch, essentially wraps Quasar Vue components with accessible python. Tons of features including SPA, FastAPI under the hood, TailwindCSS. Have used it on a few projects and started contributing recently. - Streamlit https://streamlit.io/ https://streamlit.io/ - if your goal is to get some python code set up with a GUI and deployed ASAP this is the best option. I have gone from 0 to a full working app in like an hour for some projects. Lots of love for it. A bit limited in terms of full-scale applications and large backend databases but it actually holds up really well. There are a lot of other ones that people regularly recommend. - Gradio https://gradio.app/ https://gradio.app/ - really popular with huggingface and ml folks. Similar to streamlit in that it sacrifices some level of depth for speed of standing up projects. - Textual https://www.textualize.io/projects/#textual https://www.textualize.io/projects/#textual - Building text-based UIs for the console. Seems to be pretty popular on reddit... Not to be a hater, but I have never seen a good argument for why it's worth dumping a bunch of time into this versus a web-oriented framework. They say "it's useful for products that don't need the internet", "you can use it through ssh", etc... doesn't really fit with my needs, I'll just leave it at that. - Anvil https://anvil.works/ https://anvil.works/ - a "low code" option for building python GUIs. I am pretty impressed, it has integrated databasing and a lot of plugins. If you are aiming for a scalable application for a large number of users this is probably a good options. My personal gripe with it is the number of mouse clicks it takes to do stuff but that could also be my lack of experience with the tool. - Plotly dash https://dash.plotly.com/ https://dash.plotly.com/ - not usually thought of as a full GUI library necessarily but they have options for deploying the dashboards to the web - and the overall look and feel is nice. A good option if you have a small notebook with plots that needs wider accessibility. My use cases are typically 10 - 50 users in an enterprise setting, so accessibility/low barrier to entry (pretty much meaning web-based) are concerns of mine. I also lean toward wanting to avoid learning overly-opinionated libraries (I put Qt and tkinter into this category). Why spend 50 hours learning Qt's way of building an app when I could use something like NiceGUI which lets you build a nicer looking app and gets you familiar with web dev concepts in the process. Imo a better use of my time.