WOW this is an amazing article, thanks for posting. As an aside, this popped out to me: the brain implements an algorithm not unsimilar to the TCP congestion w

WOW this is an amazing article, thanks for posting. As an aside, this popped out to me: the brain implements an algorithm not unsimilar to the TCP congestion window algo!! Perhaps I’m reading into it too much but that’s just terribly interesting. At intermediate anesthetic concentrations, neurons begin oscillating, roughly once a second, between a depolarized up-state and a hyperpolarized down-state (11). The up-state is similar to the sustained depolarization of wakefulness. The down-state shows complete cessation of synaptic activity for a tenth of a second or more, after which neurons revert to another up-state. As anesthetic doses increase, the up-state turns to a short burst and the down-state becomes progressively longer.