3 ms·
Neither of them are 5-HT2b agonists, the cardiac effects of cisapride are due to inhibition of the cardiac HERG K+ channel, but apparently this does not seem to
by freehorse 3y ago
Neither of them are 5-HT2b agonists, the cardiac effects of cisapride are due to inhibition of the cardiac HERG K+ channel, but apparently this does not seem to be as of an issue with prucalopride [1].
[1] https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2012.05011.x https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2012...