> You can explain one of the many reasons why gain of function research is necessary: anticipating next year’s version of the flu, designing drugs and vaccines

> You can explain one of the many reasons why gain of function research is necessary: anticipating next year’s version of the flu, designing drugs and vaccines such that resistance mutations reduce evolutionary fitness. If this research indeed caused the pandemic (and might cause more), do those things make the juice worth the squeeze? A chance at a better flu vaccine doesn't seem like enough reward for what we all went through.