There are some quirks, and WSL2 is buggy enough that I would advise advanced Linux users to prefer a bare metal install or a normal VM if those will work at all

There are some quirks, and WSL2 is buggy enough that I would advise advanced Linux users to prefer a bare metal install or a normal VM if those will work at all. That said, I've used the linked NixOS image under WSL every day at work for about a year, and I've been very glad to have it. Standalone Nix also works well under WSL2. I semi-regularly use it that way as well, on Ubuntu and openSUSE, for some testing at work.