Don‘t miss out the related perspective article on this: https://www.science.org/doi/10.1126/science.adi3025 https://www.science.org/doi/10.1126/science.adi3025

Don‘t miss out the related perspective article on this: https://www.science.org/doi/10.1126/science.adi3025 https://www.science.org/doi/10.1126/science.adi3025 It discusses important issues like „ A key issue for any longevity intervention is whether it causes calorie restriction (which can extend life span) or acts through independent mechanisms. Singh et al. found that taurine supplementation did not affect food intake in mice but nonetheless caused a small decrease in body weight, indicating a calorie deficit. Energy expenditure was higher in taurine-treated mice and intestinal transit time was accelerated, although it is not clear if nutrient absorption was decreased. The change in intestinal behavior is intriguing, because taurine is conjugated to bile acids to form bile salts, which facilitate uptake of dietary lipids (1). It will be crucial to control for the effects of taurine on body composition and nutrient uptake in future studies.“