Nature accepts LaTeX+PDF submissions, and will send the PDF out for review, but for final submission after acceptance, they prefer mostly-unformatted Word files

Nature accepts LaTeX+PDF submissions, and will send the PDF out for review, but for final submission after acceptance, they prefer mostly-unformatted Word files; if you submit a LaTeX+PDF final submission, they convert it to Word [1]. As they stress that authors should not bother working on the visual formatting of their final submissions, my expectation is that, internally, they then take the Word file and manually put it into their own typesetting system. Publishers like Dagstuhl Publishing that can require LaTeX submissions and use a completely LaTeX publishing workflow probably have significant efficiency advantages, but then rely on potential authors being sufficiently experienced with LaTeX that a LaTeX submission requirement doesn't drive people away. This can work well for computer science and some parts of physics, but for other fields it can be a significant burden. [1]: https://www.nature.com/nature/for-authors/final-submission https://www.nature.com/nature/for-authors/final-submission