3 ms·
You don't directly convert dosage across species like that. The dosage they tested on monkeys was 250mg/kg, and the human equivalent would be less than that.
by rale00 3y ago
You don't directly convert dosage across species like that. The dosage they tested on monkeys was 250mg/kg, and the human equivalent would be less than that.
- A_D_E_P_T 3y agoThe basic formula from mouse to human is (X mg * (3/37)) = human equivalent dose in mg/kg. In this case (1000mg * 3/37)) comes out to 81mg/kg. So, if you weigh 80kg, it comes out to 6.48 grams per day. That's a lot of taurine, but not really a crazy amount. Easy enough to consume.
- codeflo 3y agoIs there a precise biological explanation for that factor, e.g. metabolism rate or something?
- A_D_E_P_T 3y ago> oxygen utilization, caloric expenditure, basal metabolism, blood volume, circulating plasma proteins, and renal function The equation is from here: https://pubmed.ncbi.nlm.nih.gov/17942826/ https://pubmed.ncbi.nlm.nih.gov/17942826/ For what it's worth, the rat equation is (X mg * (6/37)) Keep in mind that it's a loose/general guideline. Basically a starting point. But usually a quite accurate one.
- hooo 3y agoWhen my son had cancer, many of the medication dosages were based on body surface area. Maybe it is similar to that. https://reference.medscape.com/calculator/692/body-surface-area-based-dosing https://reference.medscape.com/calculator/692/body-surface-a...
- Turing_Machine 3y agoI see that Amazon sells 1 gram capsules of taurine (several vendors). So, yeah, not too difficult to consume. One brand I saw is about $0.08/gram, so it wouldn't be overly financially burdensome, either.
- dreamcompiler 3y agoIMO anything you buy from Amazon that goes into your body should be considered at best fraudulent and at worst toxic until proven otherwise.