3 ms·
Gallimore's theory of psychedelic action, based on the predictive processing model[1] of brain function - very roughly that normal "sensory experience" is subst
by ttctciyf 3y ago
Gallimore's theory of psychedelic action, based on the predictive processing model[1] of brain function - very roughly that normal "sensory experience" is substantially the output of the brain's predictive model of reality and that when psychedelics "perturb" the model (a bit like skewing the weights in a software NN) users experience the effects of the brain scrambling to recover predictive efficacy - is fascinating to me!
He has a free 45 part course - Psychedelics and the Brain Master Course - up on youtube[2], which goes into some detail on the biochemistry and computational aspects of this.
1: https://en.wikipedia.org/wiki/Predictive_coding https://en.wikipedia.org/wiki/Predictive_coding
2: https://www.youtube.com/playlist?list=PLbqdD4EM-aEfmLvbWu8GQDhUII236MZf- https://www.youtube.com/playlist?list=PLbqdD4EM-aEfmLvbWu8GQ...