Whoa - the microbiome is hugely important for health in multiple ways. Most humans have about the same number of bacteria in their bodies as their own cells (ht

Whoa - the microbiome is hugely important for health in multiple ways. Most humans have about the same number of bacteria in their bodies as their own cells (https://www.nature.com/articles/nature11234 https://www.nature.com/articles/nature11234). I think the consensus is just the opposite as what you're suggesting - that early exposure to more things is beneficial for a healthy immune system. I suspect that the culprit is much more likely environmental contamination (microplastics, PFAS, etc), which I guess is one thing that you list. But "sterile" is not the solution, and unfortunately we have pretty badly contaminated the whole planet at this point...