A large DCFIFO array/synchronizer chain is part of the solution yes, but it's not quite a one-size-fits-all solution. Depends on if your signals are synchronous

A large DCFIFO array/synchronizer chain is part of the solution yes, but it's not quite a one-size-fits-all solution. Depends on if your signals are synchronous or asynch, and if it's a pulse or not in a single bit solution. For multibit it depends whether it's static data, whether a transfer is required every cycle, if the data needs buffering, if the data is a counter, and whether all the bits must arrive in the same cycle.