This extensive review has been available since 2006: https://nap.nationalacademies.org/catalog/11571/fluoride-in-drinking-water-a-scientific-review-of-epas-sta

This extensive review has been available since 2006: https://nap.nationalacademies.org/catalog/11571/fluoride-in-drinking-water-a-scientific-review-of-epas-standards https://nap.nationalacademies.org/catalog/11571/fluoride-in-... Neurotoxicity, especially in the presence of iodine deficiency, which is common, has been clearly documented. Toothpaste level exposure is enough to lower IQ in iodine deficiency.