5 ms·

Tooth decay is caused by acid produced by bacteria. It's too bad we can't displace the bacteria themselves instead of working downstream from that.

by Natsu 3y ago

cardamomo 3y ago
There are oral probiotics available, which aim to do just this. I'm not sure if any clinical trials have investigated their efficacy, however.
david_l_lin 3y ago
Except that we can! The oral microbiome can be modulated to get exactly what you’re asking: remove pathogens that are good at creating acid and replacing them with ones that are good at remineralizing. Shameless plug for my company (Bristle Health) that is trying to do exactly that via oral microbiome testing and personalized recommendations and products to improve.
- dharma1 3y ago
  Interesting, can you tell more? I’ve tried oral probiotics without much effect. Did notice a difference for a couple of days after taking antibiotics for a week for something else, but it quickly subsided (my regular micro biome probably quickly recolonised the mouth).
  - Natsu 3y ago
    I searched for the name and found it, seems like they ship you a test kit, then ID the microbes in your mouth and make recommendations based on that. I noticed L. ruteri in some screenshots which I already know from other probiotic uses.
- heyoni 3y ago
  You guys have anything on the market yet?
  - david_l_lin 3y ago
    Indeed we do! We have an oral microbiome test you can find here: https://www.bristlehealth.com/pages/products https://www.bristlehealth.com/pages/products and our first probiotic here: https://www.bristlehealth.com/pages/probiotic https://www.bristlehealth.com/pages/probiotic All the species in the probiotic have been clinically studied with evidence that supports improvement in the oral microbiome and reduction of oral disease. Although, for transparency, the mechanism of action of some of the probiotics is still unclear, and we're working on figuring that out to improve oral probiotics and products in the future.
darkerside 3y ago
Is there a reason we don't just rinse with a base?

Tooth decay is caused by acid produced by bacteria. It's too bad we can't displace the bacteria themselves instead of working downstream from that.

by Natsu 3y ago

Tooth decay is caused by acid produced by bacteria. It's too bad we can't displace the bacteria themselves instead of working downstream from that.

cardamomo 3y ago

There are oral probiotics available, which aim to do just this. I'm not sure if any clinical trials have investigated their efficacy, however.

david_l_lin 3y ago

Except that we can! The oral microbiome can be modulated to get exactly what you’re asking: remove pathogens that are good at creating acid and replacing them with ones that are good at remineralizing. Shameless plug for my company (Bristle Health) that is trying to do exactly that via oral microbiome testing and personalized recommendations and products to improve.

dharma1 3y ago
Interesting, can you tell more? I’ve tried oral probiotics without much effect. Did notice a difference for a couple of days after taking antibiotics for a week for something else, but it quickly subsided (my regular micro biome probably quickly recolonised the mouth).
- Natsu 3y ago
  I searched for the name and found it, seems like they ship you a test kit, then ID the microbes in your mouth and make recommendations based on that. I noticed L. ruteri in some screenshots which I already know from other probiotic uses.
heyoni 3y ago
You guys have anything on the market yet?
- david_l_lin 3y ago
  Indeed we do! We have an oral microbiome test you can find here: https://www.bristlehealth.com/pages/products https://www.bristlehealth.com/pages/products and our first probiotic here: https://www.bristlehealth.com/pages/probiotic https://www.bristlehealth.com/pages/probiotic All the species in the probiotic have been clinically studied with evidence that supports improvement in the oral microbiome and reduction of oral disease. Although, for transparency, the mechanism of action of some of the probiotics is still unclear, and we're working on figuring that out to improve oral probiotics and products in the future.

darkerside 3y ago

Is there a reason we don't just rinse with a base?