3 ms·
They're determining safety and tolerability, not efficacy. For this, they just need adequately compensated trial volunteers who take one of several different do
by dgacmu 3y ago
They're determining safety and tolerability, not efficacy. For this, they just need adequately compensated trial volunteers who take one of several different doses of the medicine and track/report symptoms, have some doctor visits, and get a lot of blood drawn. Oh, and for this one, sample urine and feces. You can read the clinical trial doc: https://clinicaltrials.gov/ct2/show/NCT05628961 https://clinicaltrials.gov/ct2/show/NCT05628961
- pgcudahy 3y agoTo get full approval they could combine this with animal efficacy studies like they did for the smallpox treatment tecoviromat, since you can’t give smallpox to trial participants either. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663070/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663070/ It turned out to be really useful to have tecoviromat for the recent mpox outbreak