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If he actually publishes any well done research - I don’t think this is such a bad thing. I suspect it’ll suffer from not having enough participants to really m

If he actually publishes any well done research - I don’t think this is such a bad thing. I suspect it’ll suffer from not having enough participants to really make great claims about what is most effective for everyone but maybe it’ll be a more effective starting point for more broad trials among the general population. Right now though, I do worry that he’s just spending money ineffectively and no one but some grifters gets anything out of this.

CameronNemo 3y ago
The problem is that the procedure described in the article is not useful for research. You effectively have a sample size of 1 or 2, which is damn near useless. All of the people being related doesn't help, either. This particular procedure just seems like a stunt.
- dragontamer 3y ago
  A study with sample size 1 is called a 'Case Study' and is used all the time in various hard sciences. Larger scale studies are of course stronger. But case studies have depth and are often the source of good hypothesis or the inspiration of other tests. ------ That being said, this dude looks like a quack to me. But the alchemists we're all quacks but still laid the foundation of modern chemistry. So it ended up all being worthwhile.
  - drekk 3y ago
    This isn't a case study. He is self reporting. With the amount of measurements he takes on himself he is bound to find something "statistically significant" by chance. p=.05 is still a 1 in 20 it's bullshit. Measure 20 variables and you'll probably find something "significant" just by chance. This dude should be called out not for being a quack or for wasting so much money. He should be called out for using his son in this way. Hundreds of thousands of Americans need plasma transfusions every year. He's doing it for fun. And objectifying his son in the process. There's a lot of exciting science happening in the anti-aging field. There's a reason researchers in the field think this is not only pointless but reckless. I've been hematoma'd. It's not fun. I would never speak to my father again if I got a hematoma or some other complication because he's afraid of his own mortality.
strken 3y ago
I wanted to make a similar comment. Anti-aging for oneself is seen as gauche or elitist, but when you think about anti-aging treatments affordable enough for all your loved ones, friends, and neighbours to use it's a lot more sympathetic. A few obsessed rich people might pave the way for the average grandparents to stay in their own home months or years longer. Aside from anything else it's also pretty cool that he's 45 and has a VO2 max above 50 along with lifting reasonably heavy weights, regardless of how old he looks. I get the feeling from looking at his website that he cares as much about the numbers as his appearance, if not more.
- youngNed 3y ago
  I mean.... i have read all the responses so far, and i'm pausing here to write this, because, i don't think anyone else has: Article: THIS MAN IS HARVESTING HIS OWN SON. HN: look at his VO2!, i wonder what he benches? insert principle skinner 'the kids who are wrong".jpeg here - but seriously HN? this isn't peak 'Weird AF' to anyone else?
  - drekk 3y ago
    I wish I could upvote this more than once. The young aren't a new commodity for nouveau riche narcissists upset about entropy. Plenty of very exciting anti-aging research going on right now without subjecting your child to plasmapheresis. For context I donate plasma twice a week. It's a 16-gauge needle and for a healthy young person like myself it takes 40 minutes or so each time. You eventually scar as your skin can't heal that quickly. People have asked me if I use heroin because of those two scars, one in each inner elbow. To think people would use something that literally already saves lives to maybe prolong their lives based on mouse trials where the mice were literally stitched together to share circulatory systems is plain evil. Please consider donating plasma if you are healthy. It does remove some PFAS from your blood if you need an incentive besides the money. It takes multiple donations to make enough medicine for one patient. "You are quite right, I changed my mind and do no longer speak of “radical evil.” … It is indeed my opinion now that evil is never “radical,” that it is only extreme, and that it possesses neither depth nor any demonic dimension. It can overgrow and lay waste the whole world precisely because it spreads like a fungus on the surface. It is “thought-defying,” as I said, because thought tries to reach some depth, to go to the roots, and the moment it concerns itself with evil, it is frustrated because there is nothing. That is its “banality.” Only the good has depth that can be radical." - Hannah Arendt

CameronNemo 3y ago

The problem is that the procedure described in the article is not useful for research. You effectively have a sample size of 1 or 2, which is damn near useless. All of the people being related doesn't help, either. This particular procedure just seems like a stunt.

dragontamer 3y ago
A study with sample size 1 is called a 'Case Study' and is used all the time in various hard sciences. Larger scale studies are of course stronger. But case studies have depth and are often the source of good hypothesis or the inspiration of other tests. ------ That being said, this dude looks like a quack to me. But the alchemists we're all quacks but still laid the foundation of modern chemistry. So it ended up all being worthwhile.
- drekk 3y ago
  This isn't a case study. He is self reporting. With the amount of measurements he takes on himself he is bound to find something "statistically significant" by chance. p=.05 is still a 1 in 20 it's bullshit. Measure 20 variables and you'll probably find something "significant" just by chance. This dude should be called out not for being a quack or for wasting so much money. He should be called out for using his son in this way. Hundreds of thousands of Americans need plasma transfusions every year. He's doing it for fun. And objectifying his son in the process. There's a lot of exciting science happening in the anti-aging field. There's a reason researchers in the field think this is not only pointless but reckless. I've been hematoma'd. It's not fun. I would never speak to my father again if I got a hematoma or some other complication because he's afraid of his own mortality.

strken 3y ago

I wanted to make a similar comment. Anti-aging for oneself is seen as gauche or elitist, but when you think about anti-aging treatments affordable enough for all your loved ones, friends, and neighbours to use it's a lot more sympathetic. A few obsessed rich people might pave the way for the average grandparents to stay in their own home months or years longer. Aside from anything else it's also pretty cool that he's 45 and has a VO2 max above 50 along with lifting reasonably heavy weights, regardless of how old he looks. I get the feeling from looking at his website that he cares as much about the numbers as his appearance, if not more.

youngNed 3y ago
I mean.... i have read all the responses so far, and i'm pausing here to write this, because, i don't think anyone else has: Article: THIS MAN IS HARVESTING HIS OWN SON. HN: look at his VO2!, i wonder what he benches? insert principle skinner 'the kids who are wrong".jpeg here - but seriously HN? this isn't peak 'Weird AF' to anyone else?
- drekk 3y ago
  I wish I could upvote this more than once. The young aren't a new commodity for nouveau riche narcissists upset about entropy. Plenty of very exciting anti-aging research going on right now without subjecting your child to plasmapheresis. For context I donate plasma twice a week. It's a 16-gauge needle and for a healthy young person like myself it takes 40 minutes or so each time. You eventually scar as your skin can't heal that quickly. People have asked me if I use heroin because of those two scars, one in each inner elbow. To think people would use something that literally already saves lives to maybe prolong their lives based on mouse trials where the mice were literally stitched together to share circulatory systems is plain evil. Please consider donating plasma if you are healthy. It does remove some PFAS from your blood if you need an incentive besides the money. It takes multiple donations to make enough medicine for one patient. "You are quite right, I changed my mind and do no longer speak of “radical evil.” … It is indeed my opinion now that evil is never “radical,” that it is only extreme, and that it possesses neither depth nor any demonic dimension. It can overgrow and lay waste the whole world precisely because it spreads like a fungus on the surface. It is “thought-defying,” as I said, because thought tries to reach some depth, to go to the roots, and the moment it concerns itself with evil, it is frustrated because there is nothing. That is its “banality.” Only the good has depth that can be radical." - Hannah Arendt