I don't have a colon (but I do still have a functioning anus). The effects from orlistat are very similar to what I experience 24/7. If you're under 30 or so, e

I don't have a colon (but I do still have a functioning anus). The effects from orlistat are very similar to what I experience 24/7. If you're under 30 or so, eventually your sphincter gets much, much stronger and the excess oil stops affecting you nearly as much. You can hold it in indefinitely until your normal "need to go" timing. This takes about a year or so to train, and you'll have quite a few accidents in the meantime. I still can't eat too much salmon in one sitting though :-( I don't get diarrhea but I do get stuck on the toilet for ages after.