Presumably the dose can be altered such that for a given individual their appetite creates a caloric equilibrium at close to the target weight. I don't think th

Presumably the dose can be altered such that for a given individual their appetite creates a caloric equilibrium at close to the target weight. I don't think this is something that is done currently. The side effects of chronic use don't appear to be that significant and would need to be weighed against the side effects of chronic obesity.