> Yet, I don't think people are right when they tell me I'm wrong to be depressed. Ah, I get the point you're making, but that's not what the article said/mean

> Yet, I don't think people are right when they tell me I'm wrong to be depressed. Ah, I get the point you're making, but that's not what the article said/meant, is it? “When they analyzed fMRI data across the whole brain, one connection stood out. In the normal brain, the anterior insula, a region that integrates bodily sensations, sends signals to a region that governs emotions, the anterior cingulate cortex. “You could think of it as the anterior cingulate cortex receiving this information about the body — like heart rate or temperature — and then deciding how to feel on the basis of all these signals,” Mitra said. In three-quarters of the participants with depression, however, the typical flow of activity was reversed: The anterior cingulate cortex sent signals to the anterior insula. The more severe the depression, the higher the proportion of signals that traveled the wrong way.” Wrong here means reversed from the norm. As in, it's not logical to argue that the mood should precede the telemetry, is it? The flow of information going the other way makes little sense from a bio-mechanistic viewpoint. That's why it's "wrong". The article makes no other judgement about (major) depression. And arguably, as we all know, it is correct to have reactive depression if some awful thing befalls us.