For backend, flask is still around, or Django if you want to go bigger. PHP is usable these days, especially with Laravel. Golang also has lots of options. For

For backend, flask is still around, or Django if you want to go bigger. PHP is usable these days, especially with Laravel. Golang also has lots of options. For frontend, vanilla JS and modern CSS go a long way. Reactivity is something you can build yourself if needed (https://news.ycombinator.com/item?id=35937464 https://news.ycombinator.com/item?id=35937464, among other examples). Though for CSS I'd like to know if there's a slightly less outdated alternative to Spectre: Something that ships a sane default design (and not just unstyled components), but isn't a giant mess like Bootstrap.