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You already hit on it. Insulin is the fat storage hormone. It triggers your fat cells to expand by absorbing sugars from the blood. But NNSs aren't absorbed by
by irthomasthomas 3y ago
You already hit on it. Insulin is the fat storage hormone. It triggers your fat cells to expand by absorbing sugars from the blood. But NNSs aren't absorbed by fat cells, so they stay in your blood longer, keeping your liver working longer, pumping out insulin. This results in diminishing insulin response over time.
- amanaplanacanal 3y agoI’ve heard this theory before, but have never seen any actual science done. If you have a pointer to any, I would love to see it!
- irthomasthomas 3y agoHere's one that tested sugar+sweetener, note the decrease in insulin clearance when sweeteners are consumed, vs just sugar: sucralose ingestion caused 1) a greater incremental increase in peak plasma glucose concentrations (4.2 ± 0.2 vs. 4.8 ± 0.3 mmol/L; P = 0.03), 2) a 20 ± 8% greater incremental increase in insulin area under the curve (AUC) (P < 0.03), 3) a 22 ± 7% greater peak insulin secretion rate (P < 0.02), 4) a 7 ± 4% decrease in insulin clearance (P = 0.04), and 5) a 23 ± 20% decrease in SI (P = 0.01). https://diabetesjournals.org/care/article/36/9/2530/37872/Sucralose-Affects-Glycemic-and-Hormonal-Responses https://diabetesjournals.org/care/article/36/9/2530/37872/Su...
- amanaplanacanal 3y agoThank you!