4 ms·

David Sinclair is considered to be a quack (bordering on a fraud) by many within the scientific community.

meowkit 3y ago
So I guess we're at the point which Harvard Medical School isn't good signal? https://sinclair.hms.harvard.edu/people/david-sinclair https://sinclair.hms.harvard.edu/people/david-sinclair Who considers him a quack? Why should I believe them?
- shpongled 3y ago
  The former dean of Harvard Medical School: https://twitter.com/jflier/status/1495833104510038026 https://twitter.com/jflier/status/1495833104510038026 A slew of retracted papers from his mentor's lab, and image duplications/fabricated western blots from David's lab: https://forbetterscience.com/2020/05/14/never-ageing-anti-aging-to-cure-covid-19/ https://forbetterscience.com/2020/05/14/never-ageing-anti-ag... https://forbetterscience.com/2023/04/17/the-original-sins-of-leonard-guarente/ https://forbetterscience.com/2023/04/17/the-original-sins-of... Several blog posts on the resveratrol controversy by Derek Lowe (required reading in pharma/biotech): https://www.science.org/content/blog-post/resveratrol-srt501-buy-now---why-wait https://www.science.org/content/blog-post/resveratrol-srt501... https://www.science.org/content/blog-post/does-resveratrol-really-work-and-does-srt1720 https://www.science.org/content/blog-post/does-resveratrol-r... https://www.science.org/content/blog-post/resveratrol-humans-results-controlled-trial https://www.science.org/content/blog-post/resveratrol-humans... https://www.science.org/content/blog-post/latest-sirtuin-controversy https://www.science.org/content/blog-post/latest-sirtuin-con... Also anecdotal, but I personally know several PIs who worked on sirtuins during their PhDs and they all say that David is full of shit.
vhcr 3y ago
You're gonna need to backup your claim, because a quick google search didn't lead me to anything.
- altvali 3y ago
  Not the person you're replying to, but this is what I found after a quick google search: Dr. Jeffrey Flier: https://twitter.com/jflier/status/1495909501211447305?s=21 https://twitter.com/jflier/status/1495909501211447305?s=21 Dr. Charles Brenner: https://twitter.com/CharlesMBrenner/status/1496604055799361537?lang=en https://twitter.com/CharlesMBrenner/status/14966040557993615... Dr. Brad Stanfield: https://www.youtube.com/watch?v=JAFnD27ffqE https://www.youtube.com/watch?v=JAFnD27ffqE
- shpongled 3y ago
  See the tweets from the other replier, as well as my reply above.

So I guess we're at the point which Harvard Medical School isn't good signal? https://sinclair.hms.harvard.edu/people/david-sinclair https://sinclair.hms.harvard.edu/people/david-sinclair Who considers him a quack? Why should I believe them?

shpongled 3y ago
The former dean of Harvard Medical School: https://twitter.com/jflier/status/1495833104510038026 https://twitter.com/jflier/status/1495833104510038026 A slew of retracted papers from his mentor's lab, and image duplications/fabricated western blots from David's lab: https://forbetterscience.com/2020/05/14/never-ageing-anti-aging-to-cure-covid-19/ https://forbetterscience.com/2020/05/14/never-ageing-anti-ag... https://forbetterscience.com/2023/04/17/the-original-sins-of-leonard-guarente/ https://forbetterscience.com/2023/04/17/the-original-sins-of... Several blog posts on the resveratrol controversy by Derek Lowe (required reading in pharma/biotech): https://www.science.org/content/blog-post/resveratrol-srt501-buy-now---why-wait https://www.science.org/content/blog-post/resveratrol-srt501... https://www.science.org/content/blog-post/does-resveratrol-really-work-and-does-srt1720 https://www.science.org/content/blog-post/does-resveratrol-r... https://www.science.org/content/blog-post/resveratrol-humans-results-controlled-trial https://www.science.org/content/blog-post/resveratrol-humans... https://www.science.org/content/blog-post/latest-sirtuin-controversy https://www.science.org/content/blog-post/latest-sirtuin-con... Also anecdotal, but I personally know several PIs who worked on sirtuins during their PhDs and they all say that David is full of shit.

vhcr 3y ago

You're gonna need to backup your claim, because a quick google search didn't lead me to anything.

altvali 3y ago
Not the person you're replying to, but this is what I found after a quick google search: Dr. Jeffrey Flier: https://twitter.com/jflier/status/1495909501211447305?s=21 https://twitter.com/jflier/status/1495909501211447305?s=21 Dr. Charles Brenner: https://twitter.com/CharlesMBrenner/status/1496604055799361537?lang=en https://twitter.com/CharlesMBrenner/status/14966040557993615... Dr. Brad Stanfield: https://www.youtube.com/watch?v=JAFnD27ffqE https://www.youtube.com/watch?v=JAFnD27ffqE
shpongled 3y ago
See the tweets from the other replier, as well as my reply above.