It goes far beyond that. By the time any real analysis is done on these data, they're extremely compressed via other file formats that extract the important si

It goes far beyond that. By the time any real analysis is done on these data, they're extremely compressed via other file formats that extract the important signal. Alignment data is stored in BAM/CRAM [1], [2] formats, and variant data in VCF [3] [1] https://en.wikipedia.org/wiki/Binary_Alignment_Map https://en.wikipedia.org/wiki/Binary_Alignment_Map [2] https://en.wikipedia.org/wiki/CRAM_(file_format) https://en.wikipedia.org/wiki/CRAM_(file_format) [3] https://en.wikipedia.org/wiki/Variant_Call_Format https://en.wikipedia.org/wiki/Variant_Call_Format