Actually a better path would have been to hack on the ClojureScript compiler that compiles to JavaScript and fork it to compile to Python, most of the core stuf

Actually a better path would have been to hack on the ClojureScript compiler that compiles to JavaScript and fork it to compile to Python, most of the core stuff is implemented with ClojureScript primitives (like seq library, collections, atoms, etc.) so there would be substantially less work starting from there.