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> It is unknown if COVID-19 vaccines have non-specific effects on overall survival > The relative mortality risk for mRNA vaccine vs. placebo was 1.03 (0.63–1.

> It is unknown if COVID-19 vaccines have non-specific effects on overall survival > The relative mortality risk for mRNA vaccine vs. placebo was 1.03 (0.63–1.71) Yet the CDC is still recommending[0] to this day that everyone 6 years and older get an mRNA vaccine; even though this article is another piece of data saying that for anyone younger than, say, 40 with no significant comorbidities (and therefore very low risk of death from Covid), you are better off not. [0]: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-t...

deleted 3y ago
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mikeyouse 3y ago
Do you ever pause to wonder why if "you are better off not" getting the vaccine if you're under 40, the CDC still recommends that everyone in that age group gets it? Perhaps your confidence in "better off not" is incorrect? Seriously, spend a few minutes looking at the vaccine effectiveness tracker -- it's still an absolute no-brainer to get vaccinated: https://covid.cdc.gov/covid-data-tracker/#vaccine-effectiveness https://covid.cdc.gov/covid-data-tracker/#vaccine-effectiven... The latest study publish in February shows this again, even with the more 'mild' strains circulating today: https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7207a3-H.pdf https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7207a3-H.pdf
- PraetorianGourd 3y ago
  Does COVID impact Europeans differently? The European equivalent to the CDC does not recommend additional boosters to those under 60[0]. I get this is a still novel virus but the divergence in guidance gives me pause, and I think that it is reasonable to step back and consider the bigger picture. [0] https://www.ecdc.europa.eu/en/news-events/ecdc-and-ema-update-recommendations-additional-booster-doses-covid-19-vaccines https://www.ecdc.europa.eu/en/news-events/ecdc-and-ema-updat...
  - mikeyouse 3y ago
    The problem comes from people misunderstanding domain-specific issues.. the CDC and ECDC largely agree here! And neither of them echo anything resembling "you are better off not" getting the vaccine if you're under 40. It's a silly premise with absolutely no support. The ECDC guidance in that link is against second boosters which would be the 4th shot in the series. The CDC's guidance is that everyone has a single shot of the "updated" vaccine which has higher efficacy against omicron/later strains -- no matter how many vaccines they've previously had. Since Europe generally had higher vaccine uptake, their level of protection is already at a higher level than the US - so the differing recommendations seem to suit the respective populations pretty well.
    - anonuser123456 3y ago
      >The CDC's guidance is that everyone has a single shot of the "updated" vaccine which has higher efficacy against omicron/later strains -- no matter how many vaccines they've previously had. The CDC is making the claim everyone should get the updated shot vs previous. They made that claim without any human trial data comparing the two. Work has been done subsequently comparing bivalent to monovalent immune response; they are about the same.
      - firstlink 3y ago
        > without any human trial data comparing the two Irrelevant distraction propaganda. It's a COVID vaccine. COVID vaccines are safe and effective. End of story.
    - PraetorianGourd 3y ago
      The United States had some of the highest vaccine acceptance rates, with the two most effective vaccines being the vast majority of doses given. The EU had 72%, USA had 69%. Not enough of a difference to attribute differing guidance to. https://ourworldindata.org/covid-vaccinations https://ourworldindata.org/covid-vaccinations
      - 3y ago
- slaw 3y ago
  So for Children Aged 3–5 Years vaccine prevented positive covid test. These were great and very useful vaccines. https://www.cdc.gov/mmwr/volumes/72/wr/mm7207a3.htm https://www.cdc.gov/mmwr/volumes/72/wr/mm7207a3.htm

deleted 3y ago

[deleted]

mikeyouse 3y ago

Do you ever pause to wonder why if "you are better off not" getting the vaccine if you're under 40, the CDC still recommends that everyone in that age group gets it? Perhaps your confidence in "better off not" is incorrect? Seriously, spend a few minutes looking at the vaccine effectiveness tracker -- it's still an absolute no-brainer to get vaccinated: https://covid.cdc.gov/covid-data-tracker/#vaccine-effectiveness https://covid.cdc.gov/covid-data-tracker/#vaccine-effectiven... The latest study publish in February shows this again, even with the more 'mild' strains circulating today: https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7207a3-H.pdf https://www.cdc.gov/mmwr/volumes/72/wr/pdfs/mm7207a3-H.pdf

PraetorianGourd 3y ago
Does COVID impact Europeans differently? The European equivalent to the CDC does not recommend additional boosters to those under 60[0]. I get this is a still novel virus but the divergence in guidance gives me pause, and I think that it is reasonable to step back and consider the bigger picture. [0] https://www.ecdc.europa.eu/en/news-events/ecdc-and-ema-update-recommendations-additional-booster-doses-covid-19-vaccines https://www.ecdc.europa.eu/en/news-events/ecdc-and-ema-updat...
- mikeyouse 3y ago
  The problem comes from people misunderstanding domain-specific issues.. the CDC and ECDC largely agree here! And neither of them echo anything resembling "you are better off not" getting the vaccine if you're under 40. It's a silly premise with absolutely no support. The ECDC guidance in that link is against second boosters which would be the 4th shot in the series. The CDC's guidance is that everyone has a single shot of the "updated" vaccine which has higher efficacy against omicron/later strains -- no matter how many vaccines they've previously had. Since Europe generally had higher vaccine uptake, their level of protection is already at a higher level than the US - so the differing recommendations seem to suit the respective populations pretty well.
  - anonuser123456 3y ago
    >The CDC's guidance is that everyone has a single shot of the "updated" vaccine which has higher efficacy against omicron/later strains -- no matter how many vaccines they've previously had. The CDC is making the claim everyone should get the updated shot vs previous. They made that claim without any human trial data comparing the two. Work has been done subsequently comparing bivalent to monovalent immune response; they are about the same.
    - firstlink 3y ago
      > without any human trial data comparing the two Irrelevant distraction propaganda. It's a COVID vaccine. COVID vaccines are safe and effective. End of story.
  - PraetorianGourd 3y ago
    The United States had some of the highest vaccine acceptance rates, with the two most effective vaccines being the vast majority of doses given. The EU had 72%, USA had 69%. Not enough of a difference to attribute differing guidance to. https://ourworldindata.org/covid-vaccinations https://ourworldindata.org/covid-vaccinations
    - 3y ago
slaw 3y ago
So for Children Aged 3–5 Years vaccine prevented positive covid test. These were great and very useful vaccines. https://www.cdc.gov/mmwr/volumes/72/wr/mm7207a3.htm https://www.cdc.gov/mmwr/volumes/72/wr/mm7207a3.htm