3 ms·

It's an amusing thought, but I don't understand how you can apply such a darwinian rulebook here unless you conflate behavioral traits with bio-molecular pathwa

It's an amusing thought, but I don't understand how you can apply such a darwinian rulebook here unless you conflate behavioral traits with bio-molecular pathways. Do you think abstinence is part of opioid resistance, or that forgetting to take pills is part of hormone resistance? Most people _not_ dying of fentanyl overdoses are not taking them in the first place, rather than surviving exposures due to sturdier nervous systems. I think a normal interpretation of the phrase "opioid resistance" would mean that their systems can tolerate a higher dosage. Conversely, most birth control failures are thought to be behavioral differences. I.e. whether the user is aware that protection may be absent due to missed doses or other scenarios called out in the instructions. Maybe these two forces will cancel out since one selects for more discipline and the other for less...

thaumasiotes 3y ago
> Do you think abstinence is part of opioid resistance, or that forgetting to take pills is part of hormone resistance? Forgetting to take pills is already part of the measured effectiveness of hormonal birth control. It's included in the official statistics. As it should be, obviously. Not taking pills is the easiest and most important way to resist their effects.
- saltcured 3y ago
  I know. I wouldn't describe that as evolving resistance to hormonal pills though...
  - thaumasiotes 3y ago
    But that's exactly what it is. Over time, willingness to take the pills, and ability to follow through on intent to take the pills, will be bred out of the population.
    - hutzlibu 3y ago
      Only if Pills were the only birth control technic. I rather hear from more and more people, how they have to struggle reproduce at all.
      - thaumasiotes 3y ago
        > Only if Pills were the only birth control techni[que]. Absolutely not. As long as they're in use, the pressure is there to make them less effective.

thaumasiotes 3y ago

> Do you think abstinence is part of opioid resistance, or that forgetting to take pills is part of hormone resistance? Forgetting to take pills is already part of the measured effectiveness of hormonal birth control. It's included in the official statistics. As it should be, obviously. Not taking pills is the easiest and most important way to resist their effects.

saltcured 3y ago
I know. I wouldn't describe that as evolving resistance to hormonal pills though...
- thaumasiotes 3y ago
  But that's exactly what it is. Over time, willingness to take the pills, and ability to follow through on intent to take the pills, will be bred out of the population.
  - hutzlibu 3y ago
    Only if Pills were the only birth control technic. I rather hear from more and more people, how they have to struggle reproduce at all.
    - thaumasiotes 3y ago
      > Only if Pills were the only birth control techni[que]. Absolutely not. As long as they're in use, the pressure is there to make them less effective.