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This is not the team's first paper on the desulfovibrio hypothesis. Their earlier 2021 paper, "Desulfovibrio Bacteria Are Associated With Parkinson’s Disease" e
by atombender 4y ago
This is not the team's first paper on the desulfovibrio hypothesis. Their earlier 2021 paper, "Desulfovibrio Bacteria Are Associated With Parkinson’s Disease" explains why they're looking at this:
> Conventional and quantitative real-time PCR analysis of feces from twenty PD patients and twenty healthy controls revealed that all PD patients harbored Desulfovibrio bacteria in their gut microbiota and these bacteria were present at higher levels in PD patients than in healthy controls. Additionally, the concentration of Desulfovibrio species correlated with the severity of PD. Desulfovibrio bacteria produce hydrogen sulfide and lipopolysaccharide, and several strains synthesize magnetite, all of which likely induce the oligomerization and aggregation of α-synuclein protein. The substances originating from Desulfovibrio bacteria likely take part in pathogenesis of PD.
Three of the researchers work for the Department of Microbiology at the Faculty of Agriculture and Forestry, University of Helsinki. Presumably they're interested in Parkinson's because farmers are known to have a much higher risk of PD than the general population?
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126658/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126658/
- anecdotal1 4y agoI'm from a small farming community in the Midwest. My father was farmer until my grandfather sold his farm when he was in his early 30s. My father developed Parkinson's and died from it a few years ago at the young age of 63. The number of farmers from our community with Parkinson's is staggering. I've been following the gut/brain theory for years. Hopefully this is going somewhere ...
- myshpa 4y ago> The number of farmers from our community with Parkinson's is staggering There are many documentaries on youtube regarding pesticides and Parkinson's (France and Germany, IIRC). Some people claim that single spill on their hand gave them Parkinson, in just few years. Those pesticides are then everywhere and in everything, even if high-end wines (makes sense, wines are supposedly sprayed upto 40? times when growing). Farming based on spraying poisons everywhere is one of the dumbest ideas of our age. > I've been following the gut/brain theory for years. Hopefully this is going somewhere ... Same.