Sure, it may evolve around it, as there already exist some strains that infect directly via the CXCR4 receptor and bypass CCR5 receptors all together. However,

Sure, it may evolve around it, as there already exist some strains that infect directly via the CXCR4 receptor and bypass CCR5 receptors all together. However, this isn't reason to not include the mutation in "designer babies". It will still be effective, and provides resistance to diseases other than HIV (though it also makes you slightly more susceptible to others). In other words, there really isn't any reason to NOT include it, especially since there is a definite benefit achieved by including it.