Yes, that dose is moderate and should have minimal adverse effects in most self-expermentalists. But we do not yet know much about possible adverse interaction

Yes, that dose is moderate and should have minimal adverse effects in most self-expermentalists. But we do not yet know much about possible adverse interactions between genetic variation and rapamycin effects—at least in terms of human subjects seeking better health and longer healthspans. We do not even have this type if data yet for mice (but stay tuned). On average rapamycin is highly effective in mice of both sexes and other species, but to the best of my knowledge there are no data yet on lifespan gains for primates like us.