Yes, the point you’re making is valid and I generally speaking agree with it. The issue isn’t necessarily that it was published in a quack journal, it’s that no

Yes, the point you’re making is valid and I generally speaking agree with it. The issue isn’t necessarily that it was published in a quack journal, it’s that now this idea has been published in a quack journal it’s “tainted” and suggesting that it be looked at again for any other reason than some significant new evidence discovered completely by accident (because you’re a quack too if you believed the idea in this paper) and it has to be pretty significant evidence too (otherwise it might look like you are cherry picking evidence for your quack belief) and only then can you consider the idea worth properly studying… all because by originally being published in a quack journal, the idea has the taint of quackery. Now most quack research is not particularly useful… but it can be made more useful to society if it’s used properly, we should be more willing to publish reproductions and failures to reproduce existing research, and we should be encouraging early career scientists in all disciplines to take this kind of quack research and to prove it wrong, it’s all there to disprove, easy done. We would get more critical thinking in our research students we would get more evidence to disprove other quack research and every now and then we might even stumble onto something good that would have gone ignored as just quackery for an unknown period of time. If we want to fix the reproduction crisis we can’t ignore the shit research papers and only reproduce the good ones we think might work, we need to be willing to look at research like this, which involves a pretty/relatively harmless high dose vitamin regimen that can be easily monitored by a clinician performing the research work (double blinds of course) and then we go from “idea that won’t be touched again and quacks try to convince people with flimsy research” to “idea conclusively proven or disproven and scientifically have settled the question without leaving reasonable doubts that can be used by quackery peddlers or others mis-using the scientific method for their own gain.