5 ms·

As someone that's been dealing with SIBO (small intestinal bacterial overgrowth), I'm confident that most diseases are the result of your gut microbiome. Reall

As someone that's been dealing with SIBO (small intestinal bacterial overgrowth), I'm confident that most diseases are the result of your gut microbiome. Really looking forward to research in this field and I hope the US starts putting more focus on phage therapy.

colordrops 4y ago
Did you take rifaximin, and did it work? I'm currently on my fourth day, and am finding that all of my joint pain has disappeared. Could be coincidental, but now there's the coincidence of this story in Science.
- hanniabu 4y ago
  Been dealing with it 3 years now, took the first 1.5 years to figure out what it was. So far took 2 rounds of rifaximin. The first round didn't do much, but the second round (with neomycin) got rid of my methane overgrowth. I still have a hydrogen overgrowth and waiting on insurance to improve another round of just rifaximin. Do you have a methane or hydrogen overgrowth?
  - pazimzadeh 4y ago
    You could try some over the counter herb-based supplements: Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/ Subjects with newly diagnosed SIBO by lactulose breath testing (LBT) were given two open-label treatment choices based upon individualized treatment preference; either two 200 mg rifaximin tablets three times daily (TID) or 2 capsules twice daily of the following commercial herbal preparations; Dysbiocide and FC Cidal (Biotics Research Laboratories, Rosenberg, Texas) or Candibactin-AR and Candibactin-BR (Metagenics, Inc, Aliso Viejo, California) for 4 consecutive weeks immediately followed by a repeat LBT. I have been taking Candibactin-AR and Candibactin-BR with my meals and have seen an improvement in my stool consistency (I have recently diagnosed SIBO/Crohn's). I was given the metronidazole for one week and it helped as well, but symptoms came back.
    - hanniabu 4y ago
      I've been taking low dose herbals as maintenance since my last round while I wait for the next round > I was given the metronidazole for one week and it helped as well, but symptoms came back. Make sure you focus on gut motility. A lot of people have it come back due to poor MMC which causes the food to sit for longer, ferment, foster the overgrowth, and cause inflammation. Here's a good thread with some options: https://www.reddit.com/r/SIBO/comments/11ac3ic/list_of_possible_measures_to_get_the_mmc_going/ https://www.reddit.com/r/SIBO/comments/11ac3ic/list_of_possi...
      - pazimzadeh 4y ago
        Thanks. I noticed that cannabis use makes it worse, and it turns out that it slows gut motility.
  - colordrops 4y ago
    Only hydrogen.
  - bigfudge 4y ago
    That sounds alike a pain to have to wait. Out of interest: when people compare US medicine with socialised medicine like the NHS, does the time spend waiting for insurance paperwork get included in comparisons?
    - hanniabu 4y ago
      Probably not. People in the USA have been brainwashed to be terrified of social programs so they'll never give them a fair comparison. They just talk about the worst cases where it takes months to be seen by the doctor, which funnily enough is exactly how it is here if you're trying to see a specialist.
mjhay 4y ago
I agree. The frustrating thing with a lot of this is that microbiota seem to follow the Anna Karenina principle: every healthy microbiota is alike, but every dysfunctional one is dysfunctional in its own way. FWIW, I have a friend whose SIBO spontaneously went into remission almost immediately after travelling to a tropical country. Of course, that probably wouldn't work for you.

colordrops 4y ago

Did you take rifaximin, and did it work? I'm currently on my fourth day, and am finding that all of my joint pain has disappeared. Could be coincidental, but now there's the coincidence of this story in Science.

hanniabu 4y ago
Been dealing with it 3 years now, took the first 1.5 years to figure out what it was. So far took 2 rounds of rifaximin. The first round didn't do much, but the second round (with neomycin) got rid of my methane overgrowth. I still have a hydrogen overgrowth and waiting on insurance to improve another round of just rifaximin. Do you have a methane or hydrogen overgrowth?
- pazimzadeh 4y ago
  You could try some over the counter herb-based supplements: Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/ Subjects with newly diagnosed SIBO by lactulose breath testing (LBT) were given two open-label treatment choices based upon individualized treatment preference; either two 200 mg rifaximin tablets three times daily (TID) or 2 capsules twice daily of the following commercial herbal preparations; Dysbiocide and FC Cidal (Biotics Research Laboratories, Rosenberg, Texas) or Candibactin-AR and Candibactin-BR (Metagenics, Inc, Aliso Viejo, California) for 4 consecutive weeks immediately followed by a repeat LBT. I have been taking Candibactin-AR and Candibactin-BR with my meals and have seen an improvement in my stool consistency (I have recently diagnosed SIBO/Crohn's). I was given the metronidazole for one week and it helped as well, but symptoms came back.
  - hanniabu 4y ago
    I've been taking low dose herbals as maintenance since my last round while I wait for the next round > I was given the metronidazole for one week and it helped as well, but symptoms came back. Make sure you focus on gut motility. A lot of people have it come back due to poor MMC which causes the food to sit for longer, ferment, foster the overgrowth, and cause inflammation. Here's a good thread with some options: https://www.reddit.com/r/SIBO/comments/11ac3ic/list_of_possible_measures_to_get_the_mmc_going/ https://www.reddit.com/r/SIBO/comments/11ac3ic/list_of_possi...
    - pazimzadeh 4y ago
      Thanks. I noticed that cannabis use makes it worse, and it turns out that it slows gut motility.
- colordrops 4y ago
  Only hydrogen.
- bigfudge 4y ago
  That sounds alike a pain to have to wait. Out of interest: when people compare US medicine with socialised medicine like the NHS, does the time spend waiting for insurance paperwork get included in comparisons?
  - hanniabu 4y ago
    Probably not. People in the USA have been brainwashed to be terrified of social programs so they'll never give them a fair comparison. They just talk about the worst cases where it takes months to be seen by the doctor, which funnily enough is exactly how it is here if you're trying to see a specialist.

mjhay 4y ago

I agree. The frustrating thing with a lot of this is that microbiota seem to follow the Anna Karenina principle: every healthy microbiota is alike, but every dysfunctional one is dysfunctional in its own way. FWIW, I have a friend whose SIBO spontaneously went into remission almost immediately after travelling to a tropical country. Of course, that probably wouldn't work for you.