3 ms·
It might not. If the build up of alpha-synuclein is rapid during COVID that might only cause a temporary issue if the person can still break it down. These peo
by FollowingTheDao 4y ago
It might not.
If the build up of alpha-synuclein is rapid during COVID that might only cause a temporary issue if the person can still break it down. These people might not go on to get Parkinson's.
Matrix metalloproteinases break down alpha-synuclein.
https://pubmed.ncbi.nlm.nih.gov/21330369/ https://pubmed.ncbi.nlm.nih.gov/21330369/
And it's cofactor, the metal that increases MMP3 activity is zinc (and calcium).
https://www.uniprot.org/uniprotkb/P08254/entry https://www.uniprot.org/uniprotkb/P08254/entry
This is why I keep screaming that zinc is probably a central deficiency to both of these disorders in some people.