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Expanding the article's scope from "we should study mice of both sexes" to boiling the ocean with "we should IDIC mice studies" doesn't help here. Invoking age
by altairprime 4y ago
Expanding the article's scope from "we should study mice of both sexes" to boiling the ocean with "we should IDIC mice studies" doesn't help here. Invoking age makes researchers more resistant to accounting for female biology in their research, because it gives them a ready excuse to say "we can't afford the combinatorial matrix of sex and age, so we're just going to study healthy adult males". In a world of theoretically infinite resources, it absolutely makes sense to widen the scope of mice studies to include all possible variations of mice, by sex and by age and by genetics. In today's actual world, it does not.
- tgv 4y agoBut then I don't see why people are willing to draw conclusions from mouse studies in the first place, certainly not medical. They don't even generalize over all mice. If anyone still takes them more seriously than a mere hint, I can't see why they would criticize them for excluding females. This study at least doesn't show much difference, and many other factors are excluded anyway.