4 ms·

Since mice are not humans the gender of the mice might be irrelevant. So much nutritional studies have been done on animals and yet we know that different anim

Since mice are not humans the gender of the mice might be irrelevant. So much nutritional studies have been done on animals and yet we know that different animals react totaly different to eg saturated fats and atherosclerosis. Animals are a garbage proxy for anything human related.

slondr 3y ago
Maybe we should be doing more invasive neuroscience research on humans.
- RaimundoLS 3y ago
  [flagged]
RobotToaster 3y ago
Unfortunately, with political correctness these days, people start whining about "ethics" and "human rights" when you experiment on human brains (fnord).
- stinos 3y ago
  Depending on what you define as 'experiment', there's quite some recent neuroscience research using invasive techniques in humans. Which as far as I'm aware is approved by an ethical committee, but that's not quite the same as 'whining' :)
morkalork 3y ago
The gender of researchers also effects outcomes: https://www.science.org/content/article/male-scent-may-compromise-biomedical-research https://www.science.org/content/article/male-scent-may-compr...
- cubefox 3y ago
  ... technically, the "sex" of the researchers.
  - morkalork 3y ago
    Well there's a potential paper right there. Take male/female researcher and pump them full of hormones and see if it also affects the mice behaviour too.
  - xwdv 3y ago
    Don’t know why you’re being downvoted. Gender isn’t a real thing biologically, it is a societal construct. It describes human behavior. So the gender role of the researcher can’t possibly have an effect on the experiment as it is imaginary. Only the sex of the researcher is what can trigger a response, as there is a biological basis.
    - red75prime 3y ago
      [flagged]
    - amanaplanacanal 3y ago
      I’ve never heard human behavior called imaginary before.
    - Chris2048 3y ago
      > it is a societal construct That has a two-way relationship with biological factors, statistically at least, meaning it's not entirely social either.
      - xwdv 3y ago
        It is 100% social.
        unaindz 3y ago
        Link to the study?
mschuster91 3y ago
> Since mice are not humans the gender of the mice might be irrelevant. Actually, it's not. It's well known that medications can have different effects or different dosage requirements depending on menstrual cycle. And if you drop out a drug candidate in animal trials because you don't account for genetic and hormonal gender as well as menstrual cycle, you can end up dropping prematurely.

slondr 3y ago

Maybe we should be doing more invasive neuroscience research on humans.

RaimundoLS 3y ago
[flagged]

RobotToaster 3y ago

Unfortunately, with political correctness these days, people start whining about "ethics" and "human rights" when you experiment on human brains (fnord).

stinos 3y ago
Depending on what you define as 'experiment', there's quite some recent neuroscience research using invasive techniques in humans. Which as far as I'm aware is approved by an ethical committee, but that's not quite the same as 'whining' :)

morkalork 3y ago

The gender of researchers also effects outcomes: https://www.science.org/content/article/male-scent-may-compromise-biomedical-research https://www.science.org/content/article/male-scent-may-compr...

cubefox 3y ago
... technically, the "sex" of the researchers.
- morkalork 3y ago
  Well there's a potential paper right there. Take male/female researcher and pump them full of hormones and see if it also affects the mice behaviour too.
- xwdv 3y ago
  Don’t know why you’re being downvoted. Gender isn’t a real thing biologically, it is a societal construct. It describes human behavior. So the gender role of the researcher can’t possibly have an effect on the experiment as it is imaginary. Only the sex of the researcher is what can trigger a response, as there is a biological basis.
  - red75prime 3y ago
    [flagged]
  - amanaplanacanal 3y ago
    I’ve never heard human behavior called imaginary before.
  - Chris2048 3y ago
    > it is a societal construct That has a two-way relationship with biological factors, statistically at least, meaning it's not entirely social either.
    - xwdv 3y ago
      It is 100% social.
      - unaindz 3y ago
        Link to the study?

mschuster91 3y ago

> Since mice are not humans the gender of the mice might be irrelevant. Actually, it's not. It's well known that medications can have different effects or different dosage requirements depending on menstrual cycle. And if you drop out a drug candidate in animal trials because you don't account for genetic and hormonal gender as well as menstrual cycle, you can end up dropping prematurely.