Yep. And even without the perceptual/disassociative/hallucinogenic aspects of heavy use, daily nitrous exposure, without long periods away, apparently interfere

Yep. And even without the perceptual/disassociative/hallucinogenic aspects of heavy use, daily nitrous exposure, without long periods away, apparently interferes with Vitamin B12 metabolism enough to cause nervous system damage. Eventual symptoms of such damage can include tingling, numbness, headaches, lethargy, balance problems, memory problems, confusion, anxiety, & depression. Even medical staff with daily exposure to sub-perceptual trace amounts (leaked or exhaled by patients) sometimes develop problems.