For story based games (with voice acting) absolutely yes. Dozens of story characters, hundreds of supporting npc and all of them talking as either part of your

For story based games (with voice acting) absolutely yes. Dozens of story characters, hundreds of supporting npc and all of them talking as either part of your missions or just to fill in the world. Maybe 50 hours is a lot for a non story based game but even then once you factor in all the sounds and all their variations to reduce repetition you might be up there.