It's an interesting question, I'm not sure. This is mentioned under the Health Risks section though: "In people who have undergone testosterone deprivation th

It's an interesting question, I'm not sure. This is mentioned under the Health Risks section though: "In people who have undergone testosterone deprivation therapy, testosterone increases beyond the castrate level have been shown to increase the rate of spread of an existing prostate cancer." So there's probably myriad scenarios where one needs to balance testosterone levels with maintaining physical activity/strength training.