3 ms·
yah that's the rub, to expose to a natural infection site while also overcoming the defenses of that site but not so much that things spin out of control. Trick
by jxramos 4y ago
yah that's the rub, to expose to a natural infection site while also overcoming the defenses of that site but not so much that things spin out of control. Tricky gambit.
But intranasal is like the pharynx and nasal passages and turbinates stuff, not all the way down in the lungs.
- DoreenMichele 4y agoThose are all interconnected.
- jxramos 4y agoyah but I think the lungs would connect more with the terminology of inhalation than intranasal. I think the language ties to different body parts, distinctions like show up in this random title I grabbed > Comparison of traditional intranasal and aerosol inhalation inoculation of mice with influenza A viruses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725743/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725743/ I suppose an intranasal agent could accidentally get inhaled, but I think it's not meant to, it would probably elicit a choking reaction and not make it very deep into the lungs. Inhaled stuff is like smoke and nebulizer things.
- DoreenMichele 4y agoWe have EENTs -- Eye, Ear, Nose, Throat doctors -- because you don't get to neatly divide up the body that way for your convenience. Just like the platypus exists because nature didn't ask humans how we wished to categorize animals before deciding nature was OK with an egg-laying mammal, even though most mammals don't lay eggs.