> given that the brain has an easier time fighting infections [than bones] This doesn't match my understanding at all, but I'm not a medical professional. As f

> given that the brain has an easier time fighting infections [than bones] This doesn't match my understanding at all, but I'm not a medical professional. As far as I know, the brain relies heavily on isolation for protection. One function of the blood-brain barrier[0] is to prevent contamination of the central nervous system from pathogens and toxins. Bacterial meningitis is treatable with proper antibiotics, but still maintains a 10% mortality rate[1]. Additionally, simple mechanical implants (e.g. plates, screws, replacement joints) don't require interfacing with the body. They are often made of solid metals which are not bioreactive (e.g. titanium) or coated with bioresistant polymers[2]. [0] https://en.wikipedia.org/wiki/Blood%E2%80%93brain_barrier https://en.wikipedia.org/wiki/Blood%E2%80%93brain_barrier [1] https://www.ncbi.nlm.nih.gov/books/NBK470351/ https://www.ncbi.nlm.nih.gov/books/NBK470351/ [2] https://en.wikipedia.org/wiki/Orthopedic_plate#Materials https://en.wikipedia.org/wiki/Orthopedic_plate#Materials