I've never really known what to make of this concern. We plan to some day colonize the moon itself. How much should we be concerned about how it will effect is

I've never really known what to make of this concern. We plan to some day colonize the moon itself. How much should we be concerned about how it will effect isolated Amazonian and Papuan tribes when the moon is lit up with a hundred points of light on the dark-crescent side as the phases shift, and one can make out the twinkle of ion drives or torch ships crisscrossing from lunar to Earth orbits? Enough to never colonize the moon?