"Cluster density, cluster location, eagerness to connect, distribution of cell types, etc. are all coded in DNA and contribute to creating "initial weights"" A

"Cluster density, cluster location, eagerness to connect, distribution of cell types, etc. are all coded in DNA and contribute to creating "initial weights"" Are they coded in DNA, or do epigenetic factors, the environment cells grow in, adjacent cells, their interaction, etc, play a role here as well?