3 ms·
Regarding plasmids, there is a similar mechanism of DNA exchange in human cells known as "gypsy transposons," that are viral fragments which were partially inte
by chasil 4y ago
Regarding plasmids, there is a similar mechanism of DNA exchange in human cells known as "gypsy transposons," that are viral fragments which were partially integrated into germline ancestry.
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009535 https://journals.plos.org/plosgenetics/article?id=10.1371/jo...
- matheusmoreira 4y agoSo retroviruses literally integrated into our biological processes and became physiological? That's seriously awesome. https://en.wikipedia.org/wiki/Retrotransposon https://en.wikipedia.org/wiki/Retrotransposon > An endogenous retrovirus is a retrovirus without virus pathogenic effects that has been integrated into the host genome by inserting their inheritable genetic information into cells that can be passed onto the next generation like a retrotransposon. > When the retroviral DNA is integrated into the host genome they evolve into endogenous retroviruses that influence eukaryotic genomes.
- chasil 4y agoI read recently that DNA transcription for protein expression is able to identify and skip an inserted element, but that the protein will be slightly different at the boundaries. It appears to have gone badly wrong for the "Tasmanian Devil." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802805/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802805/ https://www.science.org/content/article/origin-tasmanian-devil-tumors-identified https://www.science.org/content/article/origin-tasmanian-dev...