If you use Windows Pro and Enterprise, you can use GPO to disable Defender. Just run gpedit.msc and edit a few of the policies to disable real-time protection e

If you use Windows Pro and Enterprise, you can use GPO to disable Defender. Just run gpedit.msc and edit a few of the policies to disable real-time protection etc. Under Computer Configuration > Administrative Templates > Windows Components > Microsoft Defender Antivirus - Turn off Microsoft Defender Antivirus -> set to Enabled Under Computer Configuration > Administrative Templates > Windows Components > Microsoft Defender Antivirus > Real-Time Protection - Turn on behavior monitoring -> set to Disabled - Monitor file and program activity on your computer -> set to Disabled - Turn on process scanning whenever real-time protection -> set to Disabled - Turn on behavior monitoring -> set to Disabled Restart the computer and Real-time protection should be disabled permanently (until you reverse the same settings through gpedit.msc at least).