tldr; pretty different in practice, trust your doctor, all that good stuff. On some level, it is similar as they are both stimulants and nearly the same chemic

tldr; pretty different in practice, trust your doctor, all that good stuff. On some level, it is similar as they are both stimulants and nearly the same chemical. But my own research suggests the methyl group has a significant effect on how the body metabolizes the drug. The methyl group makes it fat-soluble which allows it to cross the blood brain barrier. Apparently this causes it to have an effect on dopamine and serotonin receptors which it would otherwise not - hence the euphoric effect. It also cleaves into amphetamine in the blood stream which gives it a significantly higher half-life. How you administer a drug is important, which is self explanatory. Most newer ADHD stimulants are made in such that they must be metabolized through the stomach. Additionally, the dosage is important. Meth is not only more potent, but when abused is likely to be taken in 10x (or more) amount than a therapeutic dose. So.. safe to say they are chemically similar but different in practice. This info is from my quick googling. I’m on a therapeutic dose of Adderall, and given its effect on my blood pressure I would be concerned taking meth due to all of the above. And this is why I have a doctor to help me with all of this.