>I don't have this issue with coffee in the slightest because the effect is nearly impossible to miss. The problem is not missing the effect, it's missing (lon

>I don't have this issue with coffee in the slightest because the effect is nearly impossible to miss. The problem is not missing the effect, it's missing (long term) side effects. And even large scale pharmaceutical studies miss them (you could debate if it's intentional in some cases) so it's really hard.