Typically these SPI screens only work up to 50MHz (which is already way out of spec, which is often 15MHz), there is 5M bits in 640x480x16 so you won't get more

Typically these SPI screens only work up to 50MHz (which is already way out of spec, which is often 15MHz), there is 5M bits in 640x480x16 so you won't get more than 10fps no matter what you do rendering side. Which is why they often also offer 8 bit serial interface. I guess one can use it with the PIO on rp2040. Edit: whoops it's only 320x240. Not sure how fast are they are running it.