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Yes. Here's the argument being put forth: Fructose in the diet must be metabolized by the liver, which creates excessive amounts of palmitic acid which induces
by jpxxx 15y ago
Yes. Here's the argument being put forth:
Fructose in the diet must be metabolized by the liver, which creates excessive amounts of palmitic acid which induces fat to deposit in the liver which causes abnormal insulin response which leads to metabolic syndrome (an umbrella term including diabetes and obesity) which leads to poor personal health which means poor social health which means fructose is toxic.
The science available can support this: fructose in the diet is metabolized by the liver, which at some point of saturation (in animal studies, at outrageous levels of pure fructose intake) causes excessive creation of palmitic acid which is deposited into the liver as a fat. This liver fat is moderately to strongly implicated in abnormal insulin response which can progress to diabetes which is comorbid with obesity.
Thus, actual science is a long long long long way from ~Fructose is Toxic And Must Be Removed From The Foodstream~. There's also the problem of sucrose, which immediately decomposes into… drumroll… fructose and glucose.
Glucose in this story is beyond reproach - it is the foundation of animal life. Which means that the Fructose Is Toxic hypothesis needs to take into account sucrose consumption. Which his argument doesn't.
This guy isn't completely full of shit, and I don't think his heart is in the wrong place. But he's screaming fire in a very crowded theater.
- alecco 15y ago> But he's screaming fire in a very crowded theater. That doesn't make any sense.
- jpxxx 15y agoI agree it needs work but I got bored of typing on a phone and hit send. How about "OUR FOOD IS POISONED" in a crowded newscast?
- DocSavage 15y agoYou are imagining his explanation of the biochemical pathways is the sole supporting science. That's incorrect. There are many studies supporting the direct effects of sugar, including measured lipids in students who are asked to drink sugar-laden soda vs controls. Given the many studies, he gives his hypothesis on the pathways that contribute to metabolic syndrome. Full-blown diabetes does not have to be present for there to be bad effects. Studies on the effects of hyperinsulinemia and increased insulin receptors suggest a whole list of bad outcomes, including a cellular environment that fosters cancers. He does not claim obesity is the main disease. It's another sequella of the underlying issue: excessive fructose metabolism.
- jpxxx 15y agoI like what you're saying. I'll investigate his claims with more patience and read around some more. Thank you.