His contention is that it's as toxic as alcohol, although alcohol has immediate effect on the brain and therefore is more self-limiting. You can also check out

His contention is that it's as toxic as alcohol, although alcohol has immediate effect on the brain and therefore is more self-limiting. You can also check out his video where he goes through the biochemical pathways: http://www.youtube.com/watch?v=dBnniua6-oM http://www.youtube.com/watch?v=dBnniua6-oM At one point, he asks what you call a substance that primarily gets metabolized in the liver and when presented in excess (not an extreme excess either), gets metabolized into products considered harmful to the body. I should also note that every objection you make is unsupported and ad hominem ('alarmist', 'hack science'). If you want to counter his claim, point to a study where fructose is shown not to be correlated with the diseases in question. There are certainly a lot of studies as far back as the 50s that support his claims. I personally am on the hunt for well-controlled studies with reasonable duration (years to a decade) that involve sugar/fructose.