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Did you go back to working out and protein shakes? Because if you did, you still don't know why you are reacting that way which could be masking a problem elsew

Did you go back to working out and protein shakes? Because if you did, you still don't know why you are reacting that way which could be masking a problem elsewhere, and are exposing yourself to risk. There is a reason why metabolic values have "normal" ranges. Heck, if this were a JIRA ticket, I'd want a code review!

acchow 4y ago
> There is a reason why metabolic values have "normal" ranges. The "reason" is that they assumed a normal distribution and wanted to include 95% of people. If you're outside the normal range, you are abnormal. Which doesn't necessarily mean unhealthy or that something needs to be changed, but could potentially mean that questions should be asked to understand why you are outside the range? Maybe it's totally fine, like you are an athlete or have a particular kind of diet.
- ChancyChance 4y ago
  And weight lifters are well-known for reacting calmly to anyone who challenges their regimen.
mise_en_place 4y ago
AIUI, liver enzymes being elevated don't always imply some sort of underlying liver pathology. I was on both stanazolol and test for a 3-month cycle and my liver enzymes went up. And my cholesterol inverted (LDL increased while HDL decreased significantly). I explained to my primary care doctor (not the NP who prescribes me roids) the reason for this, showing the various papers that explained the underlying cause of the issue. As soon as I discontinued stanazolol, my liver enzymes normalized as did my cholesterol. Long story short, elevated liver enzymes just mean you have elevated liver enzymes. There are cases where people have cirrhosis but they won't have elevated liver enzymes. AFAIK liver enzymes are far more useful in determining if you've had a heart attack or heart injury recently (I believe AST goes up substantially).
elevatedastalt 4y ago
Yes, my experience was very similar, and I did A/B test it. More details here—https://news.ycombinator.com/item?id=35432067 https://news.ycombinator.com/item?id=35432067 Summary: * Test after starting to work out after a long gap—elevated AST ALT, consistent with the research papers. * Test after pausing working out for 2 weeks—normal levels. * Test after working out consistently for a few months so it's no longer after a gap—normal levels.

acchow 4y ago

> There is a reason why metabolic values have "normal" ranges. The "reason" is that they assumed a normal distribution and wanted to include 95% of people. If you're outside the normal range, you are abnormal. Which doesn't necessarily mean unhealthy or that something needs to be changed, but could potentially mean that questions should be asked to understand why you are outside the range? Maybe it's totally fine, like you are an athlete or have a particular kind of diet.

ChancyChance 4y ago
And weight lifters are well-known for reacting calmly to anyone who challenges their regimen.

mise_en_place 4y ago

AIUI, liver enzymes being elevated don't always imply some sort of underlying liver pathology. I was on both stanazolol and test for a 3-month cycle and my liver enzymes went up. And my cholesterol inverted (LDL increased while HDL decreased significantly). I explained to my primary care doctor (not the NP who prescribes me roids) the reason for this, showing the various papers that explained the underlying cause of the issue. As soon as I discontinued stanazolol, my liver enzymes normalized as did my cholesterol. Long story short, elevated liver enzymes just mean you have elevated liver enzymes. There are cases where people have cirrhosis but they won't have elevated liver enzymes. AFAIK liver enzymes are far more useful in determining if you've had a heart attack or heart injury recently (I believe AST goes up substantially).

elevatedastalt 4y ago

Yes, my experience was very similar, and I did A/B test it. More details here—https://news.ycombinator.com/item?id=35432067 https://news.ycombinator.com/item?id=35432067 Summary: * Test after starting to work out after a long gap—elevated AST ALT, consistent with the research papers. * Test after pausing working out for 2 weeks—normal levels. * Test after working out consistently for a few months so it's no longer after a gap—normal levels.